Perfluorocarbon nanoemulsions with fluorescent, colloidal and magnetic properties

Noninvasive Imaging of Early Venous Thrombosis by 19F Magnetic Resonance Imaging With Targeted Perfluorocarbon Nanoemulsions.

BACKGROUND Noninvasive detection of deep venous thrombi and subsequent pulmonary thromboembolism is a serious medical challenge, since both incidences are difficult to identify by conventional ultrasound techniques. METHODS AND RESULTS Here, we report a novel technique for the sensitive and specific identification of developing thrombi using background-free 19F magnetic resonance imaging, tog...

Highly fluorescent magnetic quantum dot probe with superior colloidal stability.

A magnetic quantum dot (MQD) based cellular nanoprobe, composed of a magnetic oxide nanoparticle component and a quantum dot component, has been synthesized and used for both imaging and separation. The successful synthesis is based on a reverse micelle based polyacrylate coating in the presence of component nanoparticles, followed by their functionalization via conjugation chemistry.

Optimization of perfluorocarbon nanoemulsions for molecular imaging by 19F MRI

Multifunctional perfluorocarbon nanoemulsions for (19)F-based magnetic resonance and near-infrared optical imaging of dendritic cells.

A novel type of bimodal imaging nanoprobe based on (19)F-based magnetic resonance imaging and near-infrared optical imaging has been synthesized and applied for the labeling and imaging of dendritic cells both in vitro and in vivo.

Nanoemulsions: formation, properties and applications.

Nanoemulsions are kinetically stable liquid-in-liquid dispersions with droplet sizes on the order of 100 nm. Their small size leads to useful properties such as high surface area per unit volume, robust stability, optically transparent appearance, and tunable rheology. Nanoemulsions are finding application in diverse areas such as drug delivery, food, cosmetics, pharmaceuticals, and material sy...